Novel Synthesis of 2-Chloro-4,6-Distitutedthiocarbamido-1,3,5-Triazines

Recently in this laboratory a new route for the synthesis of 2-chloro-4, 6- distitutedthiocarbamido-1, 3, 5-triazines was developed to increase the yield of products by maintaining the purity of them and the time span required for the completion of reactions was also decreases. These are eco-friendly reactions. Novel green synthesis ofchloro-4,6-distitutedthiocarbamido-1,3,5-triazines (IIIa-e) was successfully carried out by interacting cyanuryl chloride (I) with various thiourea in (IIa-e) in 1:2 molar ratio in ethanol-acetone medium. During the synthesis parameters of green chemistry are maintained. The justification and identification of the structure of these newly synthesized compounds had been established on the basis of chemical characteristics, elemental analysis and through spectral data.