ANTIBIOGRAM OF TRADITIONAL MEDICINAL PLANT CALOTROPSIS GIGANTEA EXTRACTS AGAINST STAPHYLOCOCCUS AUREUS AND VIBRIO CHOLERAE

The increasing incidences of microbial infection and gradual rise in resistance in microbes and the available antibiotics had high-lightened the need to find more alternative antifungal and antimicrobial agents from other sources. Calotropis gigantea (Asclepiadaceae) a widely used plant that acquires number of medicinal properties and purposes includes 280 genera and 2000 species of worldwide distribution abundant in the sub-tropics and tropics, and rare in cold countries. Classifications of the degree of susceptibility or resistance of the test isolate to each antimicrobial agent (Ofloxacin and NorfloxTZ) were tested. The MIC was evaluated on plant extract, latex and antibiotics that showed antimicrobial activity. The test was performed at four different concentrations (5,10,15,20 μg/ml) of aqueous extract, ethanolic extract, latex and commercial drugs. Phytochemical screening of plant extract was also carried out.