Natural Phosphate As Solid Catalyst To Synthesis Of 1- Acetal diethyl-1H-indole-3-carbaldehyde Assisted Microwave Irradiation

Abstract - An efficient method for synthesis of 1- Acetal diethyl-1H-indole-3-carbaldehyde by combinaison of 1H-indole-3-carbaldehyde and bromoacetal diethyl using Natural phosphate doped with K2CO3 NPK2CO3 is described .The reactions promoted by microwave irradiation are advantageous in many ways because of short reaction time and solvent free reaction conditions . Several reactions of synthetic importance such as alkylation. have been satisfactorily done under microwave irradiation.