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GLUTATHIONEPEROXIDASE ANDGLUTATHIONEREDUCTASE ACTIVITY IN RETINA UNDER CONDITIONS OF EXPERIMENTAL DIABETES AND PALEOCEREBELLAR ELECTRICAL STIMULATION

Journal: NAUKA MOLODYKH (Eruditio Juvenium) (Vol.1, No. 2)

Publication Date:

Authors : ;

Page : 31-38

Keywords : streptozotocin; diabetes retinopathy; glutathioneperoxidase; glutathionereductase; electrical stimulation of cerebellum;

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Abstract

The model of sugar diabetes was induced in Wistar rats via i.p. streptozotocin (50,0 mg/kg) administration. In 1,5 months from the moment of streptozotocin the activity of glutathioneperoxidase was reduced by 42,0% and such one of glutathionereductase ? by 33,0% when compared with corresponded data in intact rats. Electrical stimulations (ES) (100 Hz) of paleocerebellum (V-VII lobules), which have been delivered during months three times per day effectively prevented the diabetes-induced reduction of activuity of antioxidant enzymes.

Last modified: 2015-12-24 22:19:51