EVALUATION OF EXPRESSION OF P16INK4A, KI-67, VEGF, E-CADHERIN IN SQUAMOUS INTRAEPITHELIAL LESIONS OF THE CERVIX
Journal: NAUKA MOLODYKH (Eruditio Juvenium) (Vol.2, No. 4)Publication Date: 2014-12-31
Authors : M.V. SHAMARAKOVA;
Page : 18-29
Keywords : squamous intraepithelial lesions; cervix; immunohistochemical markers;
Abstract
The article presents the results of a study of the functional state of squamous intraepithelial lesions of the cervix, using modern molecular biology techniques, the selection of biomarkers to facilitate the diagnosis of epithelial proliferative changes, and determine the flow of precancerous cervical conditions. The study showed that lesions with structural features of CIN2 have different malignant potential and therefore the morphological criteria of a pathological process does not reflect the nature of the biological process.
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