THE PLACE OF DELAYED HYPERSENSITIVITY TYPE TO MICROBIAL AND TISSUE ANTIGENS AT THE PREOPERATIVE PREPARATION FOR SURGICAL TREATMENT OF PATIENTS WITH GENERALIZED PERIODONTITIS

Summary. The study involved 120 patients with GP I-II degree, chronic course, in the age of 26-35 years (study group). Control group consisted of 54 patients with clinically intact periodontium. The patients of the main group were divided into subgroups: A primary (57), where the background of DTH to microbial antigens and bone in preoperative preparation scheme include specific microbial desensitization method followed by immunization; main B distinguished by the fact that this method of correction they are not carried out (due to failure patients). Specific microbial desensitization followed by immunization was carried out with the help of the adsorbed staphylococcus toxoid and streptolysin-O. According RTML patients with major groups A and B to the HRT streptococcus was found in 70,8 ± 1,81%, P <0.01 observations against 25,9 ± 0,75% in the control group. By antigen Staphylococcus ? from 49,2 ± 4,2% P <0.01, in control ? 0. We have found positive effects of the method specific microbial desensitization followed by immunization at 84,2 ± 0,23% in the main and the group. Without the use of this method (basic group B) efficiency was 39,7 ± 0,24%.