The peculiarities of penis elastic fiber in patients with erectile dysfunction and peyronie's disease

The aim of this research was to study the morphologic characteristic of penis elastic fibers in patients with erectile dysfunction (ED) and Peyronies disease (PD) by morphometric methods. Taken material was penis biopsy of 23 patients with ED and 9 patients with PD. Elastic fibers were tudied with the help of resorcinfuchsin by Veigerts and Vergofs methods. The qualitative changes of elastic fibers such as bifurcation of fibers, decolorization, cob formation, fiber thinning combining with structure thickening were detected. The decreasing of elastic fibers quantity in tunica albuginea and corpus cavernosa of penis in patients with ED and PD was noted. These elastic fibers can not be considered as physiologic fibers because they dont make their function. Their malfunction and their increasing in tissue of penis evidently lead to the deterioration of penis elasticity and erectile disorder