VALUE INTERCELLULAR interactions, extracellular matrix and vascular FACTOR IN THE DEVELOPMENT OF BREAST TUMORS

In the article on the basis of a literature review addresses current understanding of the genesis and the role of cell-cell interactions, vascular factors and extracellular matrix in a multi-step process of tumor progression. Tumor progression is characterized by increased genetic damage to cells and the growth of heterogeneity of genotypic basis, increased capacity for invasion, angiogenesis, metastasis. The importance of vascular factors in the development of breast cancer.