CYTOMEGALOVIRUS AND BACTERIAL INFECTION IN DONORS AND RECIPIENTS IN KIDNEY TRANSPLANTATION
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.23, No. 4)Publication Date: 2015-12-20
Authors : B.S. Pirov; I.I. Pikirenya; E.L. Kalmykov; O.O. Ruhmmo;
Page : 17-20
Keywords : ;
Abstract
The article is dedicated to the study of the cytomegalovirus (CMV) and other infections following the kidney transplantation regarding serological status in 164 recipients and donors. 102 (62.2%) male and 62 (37.8%) female patients were enrolled in the study, among those 82 (50%) recipients and 82 (50%) donors. There were 43 (26.2%) seronegative and 39 (23.8%) seropositive patients among donors. There were 75 (45.7%) seronegative and 7 (4.3%) seropositive patients among recipients. Immunoglobulins were used as the early serological markers of CMV infection. One third of the recipients and donors were seropositive, whilst 27 out of them had a moderate risk of post-operative complications caused by CMV infection. Lethal outcomes were more frequent in patients with high risks of post-operative complications (n=2; 1.21%). Bacterial infection was detected in 42 (70%) out of all urine samples submitted for culture tests. Antibiotic susceptibility to 2nd and 3rd generations of cephalosporins was also studied.
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