STUDY OF EXPRESSION P16INK4A, KI-67, VEGF AND E-CADHERIN SQUAMOUS INTRAEPITHELIAL LESIONS OF CERVIXJournal: I.P. Pavlov Russian Medical Biological Herald (Vol.12, No. 2)
Publication Date: 2011-06-29
Authors : M.V. Shamarakova;
Page : 11-17
Keywords : squamous intraepithelial lesions; cervix; immunohistochemical markers.;
The article presents the results of a study of the functional state of squamous intraepithelial lesions of the cervix, using modern molecular biology techniques, the selection of biomarkers to facilitate the diagnosis of epithelial proliferative changes, and determine the flow of precancerous cervical conditions. The study showed that lesions with structural features of CIN2 have different malignant potential and therefore the morphological criteria of a pathological process does not reflect the nature of the biological process.
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