AUTOIMMUNE MECHANISMS IN THE PATHOGENESIS OF THE PRIMARY OPEN ANGLE GLAUCOMA (The literature review)
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.12, No. 2)Publication Date: 2011-06-29
Authors : Sokolov V.A.; Mkhinini N.; Levanova O.N.;
Page : 109-113
Keywords : ;
Abstract
Numerous researches testify to presence of autoimmune aggression in pathogenesis POAG. Antibodies to various fabric components of an eyeball, both in forward, and in a back piece of an eye are found out. There are qualitative changes in collagenic structure of a sclera. There are products of pathological synthesis of the collagenic fibers having diagnostic, toxic, prognostic value. Change of a spectrum of immunoglobulins, cellular structure of immunocompetent cells testify that are involved in pathogenesis POAG not only autoimmune mechanisms of an autoaggression, but also change of natural immunity, and weakening of regulating functions.
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