MORPHOGENESIS ABDOMINAL AORTIC ANEURYSMJournal: I.P. Pavlov Russian Medical Biological Herald (Vol.14, No. 2)
Publication Date: 2013-06-28
Authors : Nikonenko T.N.; Nikonenko A.A.;
Page : 7-12
Keywords : ;
This paper presents data on morphological changes in the wall of abdominal aortic aneurysms in order to study the importance of the inflammatory response in the development of an aneurysm. It is found that chronic inflammation plays a major role in the pathogenesis of abdominal aortic aneurysm formation. In the wall of the aneurysm revealed extensive inflammatory infiltrates of lymphocytes, macrophages, which are the main source of metalloproteinases that cause degeneration of elastin and collagen, which leads to the destruction of the wall structure and dilatation of the aorta.
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