MYC FAMILY GENES IN SOLID-PSEUDOPAPILLARY TUMORS OF THE PANCREAS
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.14, No. 2)Publication Date: 2013-06-28
Authors : Gordienko E.N.; Pakhlina O.V.; Chekmareva I.A.; Rothin D.L.; Gorin D.S.;
Page : 13-21
Keywords : ;
Abstract
In the paper the study of molecular disorder genes c-Myc and N-Myc in solid-pseudopapillary tumor of the pancreas. Examined 24 samples of tumors obtained from 21 patients, including 19 primary, recurrent 1, 4 metastasis. Fluorescence in situ hybridization was performed using DNA samples lokusspetsificheskih to the loci 2p24, 6q23, 8q24 company ?Vysis, Abbott Laboratories Inc?, demonstrated that amplification of the N-Myc gene in solid-pseudopapillary tumor can be another confirming its neurogenic origin.
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