Nicotinic acetylcholine receptors as modulators off sympathetic neurons and sattelit glial cells protein-synthesizing systems in cranial cervical ganglion
Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.21, No. 4)Publication Date: 2013-12-20
Abstract
In the experimentally established pharmacological blockade of nicotinic cholinergic receptor type (nCR) was studied the dynamics of the content of RNA in the cytoplasm of neurons and in the sattelite glial cells cranial cervical sympathetic ganglion of rabbits. It was determined the neurotrophic nCR role in the cellular mechanisms of the ganglion, which lies in the fact that the synaptic signal through nHR has modulating effect on the activity of the protein-synthesizing system in neurons and is coordinating this activity with the metabolic activity of neighboring satellite glial cells.
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