BIOLOGY OF HUMAN DENDRITIC CELLS AND THEIR ROLE IN INFECTIOUS DISEASES

Dendritic cells are a heterogeneous human population of professional antigen-presenting cells. They are known to play a critical role in the regulation of both innate and acquired immune response. The functional activity of dendritic cells depends on the action signals microenvironment. Of particular interest is the study of the role of dendritic cells in the pathogenesis of various infectious diseases in humans.