Preliminary study on antioxidant and hepatoprotective activity of Clerodendrum phlomidis (L) against CCl4 intoxicated albino rats

Ethanolic extract of leaves, root and stem of C. Phlomidis (Verbenaceae) were prepared by continuous hot percolation. The content of total flavonoid for each extract was determined by aluminium chloride colorimetric method and the percentage content of flavonoids were determined as quercetin equivalent. The potential of drug against free radicals is evaluated by in- vitro DPPH radical scavenging assay. Hepatoprotective activity was investigated on albino rats and carbon tetrachloride (CCl4) was used to produce hepato- toxicity. Ethanolic extract of leaves showed the maximum activity, which is comparable to the standard silymarin, while other parts were found to be less significant.