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SYNTHESIS OF SIMPLE (E)-2-(2-NITROBUT-2-ENYLOXY) BENZALDEHYDE DERIVATIVES FROM (E)-(3-CHLORO-2-NITROPROP-1-ENYL) BENZENE

Journal: International Journal of Advanced Research in Engineering and Technology (IJARET) (Vol.6, No. 10)

Publication Date:

Authors : ; ;

Page : 11-16

Keywords : Iaeme Publication; IAEME; Technology; Engineering; IJARET; Baylis - Hillman Reac tion; O - Alkylation; Potassium Carbonate; THF; Nitro Compound and Salicylaldehyde .;

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Abstract

A simple and convenient synthetic route for the synthesis of ( E ) - 2 - (2 - nitrobut - 2 - enyloxy) benzaldehyde using Baylis - Hillman chlorides in presence of potassium carbonate and salicylaldehyde. Baylis - Hillman adducts derived from aldehydes and nitroethylene except the initial report by Baylis and Hillman. This strategy opens new opportunities for the preparation of libraries of a wide variety of new nitro derivatives for biological screening.

Last modified: 2016-05-30 19:20:07