Electrochemical Behaviour of Selected β-Amino Alcohols and Amino Acids

In the present work, the electrochemical behaviour of a series of 17 commercially available compounds was investigated at a glassy carbon working electrode under different conditions. The effect of specific and non?specific solute?solvent interactions affecting the oxidation potentials of the investigated compounds was confirmed by employing Modified Linear Solvation Energy Relationship (LSER) analysis. The role of ionization to the electrochemical oxidation of the investigated β?amino alcohols and their derivatives was also established, using oxidation potentials obtained at the pH values of 4.0, 7.4, 9.0 and 11.0. In all cases, a linear decrease of oxidation potential by increasing the pH was observed. Chronoamperometric signal of 300, 500 and 800 mV and radical scavenging activity towards DPPH of the compounds were further employed as additional measurements for the evaluation of their antioxidant profile. The obtained electroanalytical data imply that the β?amino alcohols, amino acids and a biogenic amine studied in this work possess moderate to strong antioxidant properties.