Complete Remission with α-Interferon in a Poor Risk Patient with Blastic Plasmocytoid Dendritic Cell Neoplasm: A Case Report and Review of Literature
Journal: Annals of Hematology & Oncology (Vol.2, No. 8)Publication Date: 2015-11-17
Authors : Mazziotta F; Caracciolo F; Orciuolo E; Buda G; Benedetti E; Bonadio AG; Iovino L; Carulli G; Ciancia EM; Azzar;
Page : 1-4
Keywords : Blastic plasmacytoid dendritic cell neoplasm; Interferon alpha; NK;
Abstract
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and clinically aggressive haematologic malignancy caused by neoplastic transformation and clonal proliferation of plasmacytoid dendritic cell precursors. Current treatment approaches are not effective and the outcome remains poor in the majority of patients even after chemotherapy and bone marrow transplantation. In this report we consider the use of interferon alpha for old unfit patients not candidate for intensive strategies.
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