Ginkgo Biloba in Alzheimer’s Disease

Alzheimer’s disease (AD) is a chronic and most prevents disease, affecting millions of people worldwide and causes a great burden to the society. Besides hyperphosphorylated tau and neurofibrillary tangles, various other mechanisms like oxidative stress, mitochondrial dysfunctions, Aβ production, neurofibrillary tangle accumulation, calcium mishandling, and hormonal imbalance also play a role in causing the neuronal loss and the disease process. Various studies have shown a beneficial role of ginkgo biloba in Alzheimer’s disease, although some have refuted its role in AD. In the absence of effective therapy in dementia particularly in AD, Ginkgo biloba seems to have a therapeutic value in dementia and it needs further clinical trial to recommend it as an effective drug in AD. In this review various studies pertaining to the role of ginkgo biloba on memory and various mechanism of action of ginkgo biloba in improving memory function have been discussed.