Pancreatic Neuro-Endocrine Tumor A Case Report Review of Literature

A 14-year-old boy was evaluated for a large mass in the head of pancreas and underwent Whipples procedure with saphenous vein patch repair of the Superior mesenteric-portal vein confluence. The final histo-pathology report was a well differentiated neuroendocrine carcinoma of the pancreas. The clinical presentation, operative post operative management is discussed.Pancreatic NeuroEndocrine Tumors(PNETs) are rare malignancies and compared to adenocarcinomas they have an indolent course with better prognosis. Malignant PNETs constitute one percent of pancreatic cancers by incidence 10 percent of pancreatic cancers by prevalence. They are clinically classified as non-functioning functioning tumors (hormonomas). The mainstay of treatment is complete excision. Pathological features, Immunohistochemical studies genetic analysis play a role in the management of these tumors with recent developments in the management of advanced tumors with targeted therapy somatostatin analogues biological agents.