ESTIMATION OF SERUM TOTAL PROTEIN LEVELS IN PATIENTS WITH ORAL CANCER- A STUDY

Background and Objectives The present study was conducted to estimate the serum levels of Protein in patients with oral cancer, compare these values among patients with oral cancer and normal subjects and to correlate the values among clinical and histological grades in oral cancer. Materials and Methods The study consisted of 30 oral cancer patients and 30 normal subjects. Diagnosis of oral cancer was based on clinical and histopathologic findings. The patients were grouped clinically according to TNM staging given by American Joint Committee on Cancer and histopathologically as per the Broder’s classification. Serum levels of protein were estimated using semiautoanalyser and data was statistically analysed. Data analysis was carried out using Statistical Package for Social Science (SPSS, V 10.5) package. Results Study showed no change in serum levels of protein in patients with oral cancer compared to that of normal subjects. The mean serum levels of protein showed no change through clinical stages and histological stages of oral cancer. Conclusions and Clinical Significance However our study showed no change in serum levels of protein in patients with oral cancer compared to that of normal subjects. But to validate the above results further studies on large sample size are required.