PRIMARY OVARIAN CARCINOID TUMOUR WITH ISOLATED TRICUSPID REGURGITATION -CASE REPORT

Carcinoid tumours are rare slow growing neoplasms that arise from neuroendocrine cells. Primary ovarian carcinoid tumours are rare, forming 0.3 percent of all carcinoid tumours. Carcinoid heart disease due to ovarian primary is very rare. A rare case of primary ovarian carcinoid tumour with isolated tricuspid regurgitation is presented. The patient had pelvic mass and was operated for clinical suspicion of ovarian tumour. A large solid yellowish tumour of size 12 cm was seen completely replacing the right ovary. Differential diagnosis of granulosa cell tumour and carcinoid tumour were considered histopathologically. Immunohistochemical study of the tumour showed positivity for Chromogranin and synaptophysin. No tumour was detected elsewhere by abdominal Ultrasonograhy and CT scan confirming the diagnosis of primary ovarian carcinoid tumour. Post operative review of the case details showed isolated tricuspid regurgitation on routine pre operative echocardiograph. The most common cardiac manifestation of carcinoid heart disease is tricuspid insufficiency. It is important to be aware of carcinoid tumour in the pathological diagnosis of ovarian tumours, even in the absence of any clinical indicator of carcinoid syndrome, as it carries a better prognosis and clinical outcome in comparison with most other malignant ovarian tumours.