PORTAL VEIN THROMBOSIS- INTERESTING CASE SCENARIOS

Portal vein thrombosis (PVT) refers to obstruction of blood flow in portal vein and its branches due to thrombus. Its prevalence in cirrhosis ranges from 5-15 and accounts for 5-10 of cases of portal hypertension1. PVT can occur in two clinical entities, can be acute or chronic PVT.The clinical features and management differs between acute and chronic. Cause of PVT in cirrhosis is due to reduced portal vein blood flow, endotoxemia, acquired and inherited thrombophilic conditions. Risk factors for PVT can be local and systemic. Local risk factors include malignancies of abdominal organ most commonly pancreatic and hepatocellular carcinoma accounts for 21-242, 3. Others include cirrhosis, appendicitis, pancreatitis, cholecystitis, diverticulitis, IBD or following surgeries such as colectomy, cholecystectomy, gastrectomy, liver transplantation, TIPS. Other thrombotic risk factors include Myeloproliferative disorders30-404, Factor V Leiden mutation, Protein C and S deficiency, Antiphospholipid syndrome, OCP, pregnancy. We present interesting case scenarios of PVT detected in three different clinical situations such as Essential thrombocytosis, Appendicitis, Pancreatitis.