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Journal: Indo American Journal of Pharmaceutical Sciences (IAJPS) (Vol.04, No. 02)

Publication Date:

Authors : ; ; ; ; ; ;

Page : 336-341

Keywords : Hypertension; Insulin and Hyperinsulinemia.;

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OBJECTIVE: To determine the frequency of hyperinsulinemia in patients with essential hypertension. PATIENTS AND METHODS: This cross sectional study of six months was conducted from July 2016 to December 2016 at LUMHS Jamshoro Sindh Pakistan. All the patients with essential hypertension were evaluated for serum insulin level by taking fasting 2 ml venous blood sample and send to laboratory for analysis. The frequency / percentages (%) and means ±SD computed for study variables. RESULTS: During six months study period, total seventy two (47 males and 25 females) patients of essential hypertension were screened for hyperinsulinemia. The mean age ± SD for whole population was 48.97±5.98 while the mean serum fasting insulin level in hyperinsulinemic and normoinsulinemic was 35.87±8.65 and 20.76±3.72 respectively. The hyperinsulinemia was observed in 45 (62.5%), of which 31 (68.9%) males and 14 (31.1) females. Regarding complications 53 (73.6%) had ischemic heart diseases and 19 (26.3%) had history of stroke. CONCLUSION: Hypertensive individuals had hyperinsulinemia that fluctuates with duration of hypertension and associated complications Key words: Hypertension, Insulin and Hyperinsulinemia.

Last modified: 2017-03-11 23:09:57