Butterfly pattern hypopigmentation with antitubercular treatment

Standard short course chemotherapy is the key element of the DOTS strategy and these drugs cause different kinds of cutaneous adverse drug reactions that usually occur within 2 months of initiation of treatment in around 97% of the patients. We hereby report a case of a 16-year-old female patient who developed butterfly pattern hypopigmented rashes after 3 months of starting on category 1 antitubercular treatment (ATT). Other causes with similar picture were ruled out with additional investigations and the case was confi rmed as ATT induced hypopigmented rash. WHO-UMC causality assessment showed a probable association. [Int J Basic Clin Pharmacol 2014; 3(2.000): 410-411]