PROSTATIC CANCER IN PATIENTS PRESENTING WITH LOWER URINARY TRACT SYMPTOMS

Objective: To see the incidence of prostatic cancer in patients presenting with lower urinary tract symptoms. Patients and Methods: The one year descriptive case series study was conducted in the department of Urology - Liaquat University Hospital Jamshoro / Hyderabad. A total of 100 patients of age more than 50 years had lower urinary tract symptoms were included. The complete blood count (CBC), blood urea, serum creatinine, serum electrolytes,prostate specific antigen (PSA), random blood sugar (RBS), ultrasound abdomen and pelvis and prostatic biopsy were taken if required. The data variables with measurement scale were presented by their mean ± standard deviation and incidence of prostatic cancer was presented as percentages. Results: Incidence of prostate cancer in patients presenting with lower urinary tract symptoms was observed in 8.0%. Significant association of prostate carcinoma was observed with age groups, IPSS score, prostate weightandserum PSA level. Conclusion: It is concluded that our findings have implications for clinical practice: as the value of population-based PSA screening has yet to be demonstrated in randomized controlled trials. LUTS severity should not be used as a sole criterion of whether or not to screen for early prostate cancer. Key Words: Prostatic carcinoma, Lower urinary tract symptoms, Transrectal ultrasound sonography, Digital rectal examination, Biopsy