REVIEW ON MUCOADHESIVE BUCCAL DRUG DELIVERY SYSTEM

Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Mucoadhesive drug delivery system shows promising future in enhancing the bioavailability and specific needs by utilizing the physiochemical characters of both the dosage form and the mucosal lining. It has to be noted that only a moist surface can bring the muco-adhesive nature of the dosage form.