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Catalyst and solvent-free synthesis of β-enaminone derivatives

Journal: Asian Journal of Green Chemistry (Vol.2, No. 4)

Publication Date:

Authors : ; ; ;

Page : 299-306

Keywords : ;

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In this study, the green procedure for synthesis of the β-enaminones is described. The reaction of aromatic amines with β-dicarbonyl compounds under solvent and catalyst-free conditions at 120 °C affords the β-enaminone and β-enamino esters in high-to-excellent yields, in short reaction time, easy separation, work up and purification without need to column chromatography. Also, some new derivatives of β-enaminones were synthesized using this method. The prominent advantages of this new method is operational simplicity, good yields in short reaction times, easy work-up procedures, catalyst and solvent free condition.

Last modified: 2018-07-17 04:14:47