In vitro anti-cancer activity of Piper betel leaf extract on HA -29 and its anti-oxidant activity

Wayanad is a land with a luxury of flora and fauna. These repositories could be utilized by the reaserchers those who are interested. Here we used the Piper betel leafs collected from Wayanad district, Kerala against Colon cancer which is one of the best understood neoplasms from genetic perspective. Yet it remain the second most common cause of cancer related death, indicating the some of its cancer cells are not eradicated by current therapies. It is reported that some herbs protect the body from cancer by enhancing detoxic functions of the body. The detoxification, anti-oxidation, anti-mutation, anti-diabetic, cardiovascular, anti-inflammatory / immunomodulatory, anti-ulcer, hepato-protective and anti-infective properties of betel leaves also explored. In this study we examined inhibition of HA- 29 cell proliferation by piper betel leaves. The LD 50 value 98.4442-µl/ml possess good anticancer activity against colon cancer cell lines (HT- 29). The anti-oxidant activity of piper betel leaf extract also analyzed. Dinesh M. D | Neethu George | Abdul Bari. K. K | Hima K. U | S. Meenatchisundaram"In vitro anti-cancer activity of Piper betel leaf extract on HA -29 and its anti-oxidant activity" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-4 , June 2018, URL: http://www.ijtsrd.com/papers/ijtsrd12926.pdf http://www.ijtsrd.com/biological-science/microbiology/12926/in-vitro-anti-cancer-activity-of-piper-betel-leaf-extract-on-ha--29-and-its-anti-oxidant-activity/dinesh-m-d