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Development and Validation New Analytical Methods of Levofloxacin in IV Infusions by UV-Visible spectrophotometric Methods and Determine Assay, % Purity and Stability in Three Marketed Brands

Journal: International Journal of Science and Research (IJSR) (Vol.3, No. 6)

Publication Date:

Authors : ; ;

Page : 960-963

Keywords : Levofloxacin; uv; visible; Assay; Purity; Stability;

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The present study was undertaken to develop and validate a simple, accurate, precise, reproducible and cost effective UV-Visible spectrophotometric method for the estimation of levofloxacin in bulk and pharmaceutical formulation in three different Brands of cipla lkem,pdpl throught the experiment the solvent used for uv method was water and the absorption spectra was carried out at 288nm and forvisible method reagent used is 2,4 DNP in methanol and determination carried out at 510 nm. The concentration ‘range is 2-10?g/ml. The method was shown linear in the mentioned concentrations with correlation coefficient of R20.9999. The %purityof levofloxacin is 97.4%-115.2%. The percent relative standard deviation (RSD %) of method precision and intermediate prescision is

Last modified: 2014-06-24 20:35:02