Sympathetic Skin Response in Children with Iron Deficiency Anemia

BACKGROUND Iron deficiency anemia IDA is particularly high in children in developing countries .Sympathetic skin response SSR is a polysynaptic reflex, and its final efferent pathway involves pre- and post-ganglionic sympathetic sudomotor fibers that ultimately activate the sweat glands through sympathetic outflow . The aim of this study was to investigate whether IDA is involved in SSR. METHODS 24 patients 17 girls, 7 boys with IDA and 20 healthy children 11 girls, 9 boys were enrolled in the study. RESULTS Significant differences were observed between the palmar SSR results latency, ms of the patient and the control groups 1.09±0.24, 0.92±0.30, p= 0.048 . There was no correlation between ferritin levels and SSR results of the patient group p=0.65 . CONCLUSIONS The evidence from this preliminary study suggests that efferent C fibers of the sympathetic nervous system may not intact in IDA. The sudomotor autonomic function test may be useful to detect autonomic involvement earlier. Abdurrahman Sönmezler | Mahmut Abuhandan | Tahir Kurtulus Yoldas | Yesim Oymak | Mustafa Çalik | Bülent Güzel | Hakim Çelik "Sympathetic Skin Response in Children with Iron Deficiency Anemia" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-2 , February 2019, URL: https://www.ijtsrd.com/papers/ijtsrd21593.pdf