Alterations of Hematological and Biochemical Profile of Calves Infected Naturally with Tropical Theileriosis | Biomedgrid

Background: Bovine theileriosis in cattle is a disease caused by protozoan parasite known as Theileria annulata, transmitted by ticks of genus Hyalomma. More than 250 million domestic cattle have been estimated to be at risk. This disease leads to severe losses in production and reproduction of cattle. The present study is performed to investigate the effect of Theileriosis on serum hematological and biochemical profile of calves, as a supportive aid tool for diagnosis of the disease and to figure out any kind of symptomatic treatment to support animal health to reach complete recovery. Materials and Methods: 30 crossbred, 3 months age average Calves were purchased from Keynana company (White Nile state), prior to purchase they were tested for thieleriosis, blood samples were collected and screened by blood smear and confirmed by IFAT, and finally by PCR. Calves were moved to Khartoum state and allocated in a farm recorded positive theileriosis infections previously with noticeable presence of ticks. Samples collected in a period started from January to March 2016 depending on appearance of high body temperature (40ºC), enlargement of lymph nodes and any other sign or symptom related. Samples were tested as described before. Results: Positive samples showed pronounced reduction in Hb, PCV, and RBCs, WBCs count 10.1±0.75, 27.6±2.8, 6.0±2.3 and 2.7±1.2 respectively. While the biochemical profile revealed significant low level of serum total protein, albumin and phosphorus. Whereas liver enzymes elevated significantly, ALT, AST, GGT 53.2±8.9, total bilirubin 4.6±0.08 and direct bilirubin 4.3±0.12. While creatinine, and glucose values, were not significantly different between pre and post infection. Conclusion: Hematological and biochemical profile of calves after theileriosis infection was tremendously influenced, so it could be a considerable tool for tentative diagnosis of tropical theileriosis (Figure 1).