Phenhylephrine Hydrocloride Gastro Retentive Floating Matrix Tablets Design and in Vitro Evaluation

The objective of this research is to obtain sustained release of Phenylephrine hydrochloride. In this research work combination of natural and synthetic gums were used in different ratio to get sustain release different gas generating agents were used to float the tablet. Prepared powder blend is subjected to pre formulation studies. Then prepared tablet were evaluated for different evaluation tests. Finally dissolution data was subjected to various release kinetic models to understand release mechanism of drug. Sujit Ubale | Tejasvee Shinde | Adnan Shaikh "Phenhylephrine Hydrocloride Gastro Retentive Floating Matrix Tablets: Design and in Vitro Evaluation" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-6 , October 2019, URL: https://www.ijtsrd.com/papers/ijtsrd29144.pdf Paper URL: https://www.ijtsrd.com/pharmacy/pharmaceutics/29144/phenhylephrine-hydrocloride-gastro-retentive-floating-matrix-tablets-design-and-in-vitro-evaluation/sujit-ubale