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The role of TLR4 in up-regulation of autophagy-related protein and MMP9, MMP14 expression via EMMPRIN stimulated THP-1 macrophages

Journal: Journal of Cardiovascular Medicine and Cardiology (Vol.6, No. 4)

Publication Date:

Authors : ; ;

Page : 082-087

Keywords : TLR4; Extracellular matrix metalloproteinase inducer; Autophagy; Matrix metalloproteinases; Coronary heart disease;

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This study investigated the mechanism of toll-like receptor 4(TLR4) in up-regulating autophagy-related protein and matrix metalloproteinase 9(MMP9), MMP14 expression in THP-1 macrophages which were stimulated by Extracellular Matrix Metalloproteinase Inducer (EMMPRIN). So that exploring its importance in the progression of Coronary Heart Disease (CHD).

Last modified: 2019-12-24 20:59:17