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Journal: Journal of the Grodno State Medical University (Vol.17, No. 5)

Publication Date:

Authors : ;

Page : 506-511

Keywords : haemophilia; haemophilic arthropathy; chemical synoviorthesis; total knee replacement;

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Background. The main clinical manifestations of hemophilia are spontaneous hemarthrosis and haemophilic arthropathy. Currently (since 2009) two hemostatic therapy regimens are employed in Belarus – «on demand» and prophylactic ones. The purpose of this research was to clarify the influence of different types of hemostatic therapy on the development of hemophilic arthropathy and to determine the effectiveness of chemical synoviorthesis and total knee replacement (TKR). Material and methods. A retrospective analysis of the therapy and its results in 87 patients with severe hemophilia treated at the Belarusian Research and Practical Center of Traumatology and Orthopedic Surgery and Belarusian Research Center for Pediatric Oncology, Hematology and Immunology during 2009-2018 years was performed. Results. The obtained findings showed that prophylactic hemostatic therapy prevented the development of haemophilic arthropathy. In the patients treated "on demand" the progression of haemophilic arthropathy could be slowed down by chemical synoviorthesis; in the cases of its later stages the operation of choice was TKR.

Last modified: 2020-01-08 17:05:26