PLACENTAL SITE TROPHOBLASTIC DISEASE IN A YOUNG WOMEN - A RARE CASE REPORT

We present a case of para1 living 1 women who presented with an 18 month history of amenorrhea after normal vaginal delivery. Associated with abdominal pain, distension for 1 week duration. She was observed with slight elevation of serum Beta-hCG level, an enlarged heterogenous uterus with a flushy mass of 4x3cm size in the anterior vaginal wall with areas of ulceration. An biopsy was performed, and the patient was diagnosed with placental site trophoblastic tumor, the patient then underwent surgery. Placental site trophoblastic tumor is the rarest form of gestational trophoblastic disease, derived from intermediate trophoblast cells. It does not have a pathognomonic appearance, therefore correlation with medical history, as well as results of laboratory tests and pathological analysis is mandatory. It is a relatively chemoresistant tumor, posing considerable therapeutic challenges, patients with localized disease are managed with surgery and those with metastatic disease require additional chemotherapy. Herein, we review the main features of this entity as the rarity of this tumor is associated with imaging and pathological pitfalls, reinforcing the need for further experience in this field.