ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

Physiological correlates of neuro- and magnetic stimulation in therapy of epilepsy

Journal: I.P. Pavlov Russian Medical Biological Herald (Vol.28, No. 1)

Publication Date:

Authors : ;

Page : 88-98

Keywords : vagus and trigeminal nerves stimulation; transcranial magnetic stimulation; magnetic field; epilepsy;

Source : Downloadexternal Find it from : Google Scholarexternal


In the literature survey, non-pharmaceutical methods of therapy of epilepsy are considered including electrostimulation of vagus nerve, exposure to magnetic field and transcranial magnetic stimulation (TMS). Correlates of the effectiveness of electro- and magnetic stimulation are electrophysiological parameters, clinical data and influence on the mental and cognitive functions. Use of repetitive transcranial magnetic stimulation in addition to antiepileptic drugs has a certain ground. According to modern understanding and the results of experimental studies, the mechanism of modulator inhibitory alterations is associated with a potential of TMS to cause long-term synaptic depression or long-term potentiation. These long-lasting phenomena probably underlie anticonvulsant effects of low frequency magnetic stimulation. Inclusion of physiologists and neurophysiologists into the research will permit to solve such an important problem as a study of physiological mechanisms of the effectiveness of non-pharmacological electro- and magnetic action in epilepsy.

Last modified: 2020-04-10 22:53:37