ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

Evaluation of Safety Parameters of Ayurvedic Antimicrobial Formulation for Treatment of Vaginitis during Acute and Chronic Oral Toxicity and Vaginal Irritation Studies in Animal Models

Journal: International Research Journal of Pharmacy and Medical Sciences (IRJPMS) (Vol.2, No. 4)

Publication Date:

Authors : ; ; ;

Page : 25-34

Keywords : ;

Source : Downloadexternal Find it from : Google Scholarexternal


This in vivo preclinical toxicity study has been done to standardize a new vaginal herbal formulation consisting of dried parts of the stem barks of Azadirachta indica A. Juss. and Saraca asoca Roxb. who find mention in many Ayurvedic medicine texts for treatment of vaginitis. Both Acute and chronic toxicities of its hydro alcoholic (30:70) extract have been evaluated using the oral as well as vaginal route of administration through haematological and histopathological studies of the stomach, liver, and kidney. Vaginal irritation test has been also done to assess the redness, ulceration, bleeding, etc., during drug administration.

Last modified: 2020-06-16 17:59:11