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Journal: Journal of the Grodno State Medical University (Vol.18, No. 4)

Publication Date:

Authors : ; ; ; ; ;

Page : 375-381

Keywords : measles; immunity tension; age groups;

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The goal is to evaluate the immunity against measles in the population of Grodno and the Grodno region with diagnostic kits from various manufacturers. Material and methods. Population immunity against measles among 1324 individuals from the Grodno region was investigated. The determination of serum IgG was carried out using ELISA kits from two manufacturers: “Vector Best“(Russia) and “VirionSerion” (Germany). Results and conclusions. The level of the population immunity established by the “VirionSerion” (84.6%) and “Vector Best“ (70.7%) kits was below the threshold level (90-95%), sufficient to block the epidemic process. The most vulnerable age groups are people from 6 to 15 and those from 16 to 40 years old, which makes it expedient to carry out repeated vaccine prophylaxis in case of complications of the measles epidemic situation as well as to conduct additional study of the reasons for absence or low immunity indicators for each child who has undergone vaccination. Differences in the rates of detection of IgG antibodies to measles obtained while using kits from various manufacturers are probably associated with different specific activity of these kits. In connection with the severity of the measles epidemic in the neighboring states, it is advisable to monitor population immunity in people belonging to high-risk groups and periodically conduct a survey of representative groups from the entire population.

Last modified: 2020-10-05 22:43:07