Overview of Determination of Doxazosin Levels in Pharmaceutical Preparations and Biological Matrix

Doxazosin is an alpha-adrenergic antagonist that selectively inhibits the alpha-1 subtype commonly used to treat hypertension and benign prostatic hyperplasia. Determination of doxazosin levels in pharmaceutical preparations and biological matrices needs to be known more deeply. This review gathered information on analytical methods for the determination of doxazosin in pharmaceutical preparations and biological matrices. Information gathering was conducted with Google Scholar from 2000-2020. The results showed that the analysis method of doxazosin could be classified into spectrophotometric methods and chromatographic methods. These two groups of methods are described in more detail in this article. This article is useful for researchers and scientists involved in developing new analytical methods or formulations for doxazosin.