Effect of Art Increasing Hemoglobin in Human Immunodeficiency Virus-Infected Patient with Anemia at Wangaya Hospital in 2018-2020

Background: Anemia is most common hematologic abnormalities among people living with HIV/AIDS (PLWHA) is frequently associated with poor quality of life and poor prognosis. It has been well described who taking ART dan non ART regimens. In addition, we have discussed on relationship between PLWHA with anemia with before taking ART and after taking ART. Methodology: We conducted observational analitic with follow up study design use medical record data during 2018 to 2020 from PLWHA with anemia at Wangaya Hospital, in Denpasar, Bali, Indonesia taking ART for at least 3 months. We excluded PLWHA with impaired hemoglobin level causes renal failure, thalassemia, aplastic anemia, bleeding, pregnant woman. The data were analyzed using SPSS software for windows version 24.0. McNemar test was done, with p value of < 0.05 was considered statistically significant. Results: A total of 426 PLWHA, the overall effectiveness of ART 318 (74.6 %) samples were reported increasing hemoglobin level but 108 (25.4 %) samples with decreasing hemoglobin level. There is significant association statistically between patient’s anemia status before and after ART (p < 0.001). Conclusion: This study has shown that PLWHA with anemia before taking ART and after taking ART significant increasing hemoglobin level. A statistically significant association was observed between ART therapy and increasing hemoglobin level.