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An Efficient Synthesis for Novel 2, 3-Disubstituted -4-Thiazolidones and Antimicrobial Evaluation

Journal: International Journal of Science and Research (IJSR) (Vol.10, No. 4)

Publication Date:

Authors : ;

Page : 905-908

Keywords : 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone; 2; 3-Disubstituted-4-thiazolidones;

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Novel 2-Methyl (2?-hydroxy-3?/5?-chloro-5?/3?-chloromethyl phenyl)- 3-( 3?/4?-sustitutedphenyl)-4-thiazolidones are synthesized from 2-Hydroxy-3/5-chloro-5/3-chloromethyl acetophenone in good yield with purity. The structure of these compounds are confirmed by IR, 1H NMR and Mass spectra of a representative member from the series .These novel derivatives are then screened for antibacterial and antifungal activities against S.aureus, E.coli, X.citri, E.carotovora, C.albicans, T.rubrum, A.solani and H.turcicum.

Last modified: 2021-06-26 18:50:05