Association between Total Bilirubin Levels and Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus

Aims- To investigate the association between Total Bilirubin levels and Diabetic Retinopathy in patients with Type 2 Diabetes Mellitus. Material and Methods - In this prospective,randomized study, a total of 60 diabetic patients presenting to Subharti Hospital, Meerut were divided in following categories 1. Mild Non-Proliferative Diabetic Retinopathy (NPDR). 2. Moderate NPDR. 3. Severe NPDR 4. Proliferative Diabetic Retinopathy (PDR) 5. No DR The eye with worse retinopathy was chosen for inclusion in the study examinations. If both eyes had equal retinopathy, the right eye was assigned to the study. Cases were followed up at 1 week, 1 month and 6 months after first visit. Serum total bilirubin levels were measured at each follow-up visit. Observation and Result- On correlation analysis, the two variables Diabetic retinopathy Fundus grading and Total Serum bilirubin levels are inversely and significantly correlated at baseline, 1 week, 1 month and 6 months. Conclusion- Serum bilirubin concentration is inversely and independently associated and inversely correlated with the prevalence of DR.