Review on Preformulation - Study of DrugJournal: International Journal of Science and Research (IJSR) (Vol.9, No. 9)
Publication Date: 2020-09-05
Authors : Anand S More;
Page : 1090-1094
Keywords : Preformulation Parameters; Solubility; Bulk Properties; Stability Studies;
Preformulation phase is a critical learning time about the physicochemical properties of drug candidate, these studies are mainly deals with the effect of change in physicochemical properties on the drug formulation prior to its developement. It has significant impact on manufacturing, storage and performance of drug product so one can avoid such problem through the proper preformulation studies of drug. It mainly includes intrinsic solubility studies, derived properties of the powder, importance of partition coefficient and much more. With these studies Formulator can able to select best drug candidate for development of new bioavailable dosage form. So these article give you a brief idea about such studies which are commonly carried out by formulator companies.
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Last modified: 2021-06-28 17:11:32