IgM Profile of Patients Suspected to Have Toxoplasmosis among Bad Obstetrics History Group Attending at Integral Institute of Medical Science&Research, Integral University, Lucknow

Toxoplasmosis is caused by an obligate intracellular parasite i. e. Toxoplasma gondii. It is a pathogen of TORCH group which is responsible of congenital infection. TORCH is comprising of Toxoplasma gondii, Rubella, Cytomegalovirus (CMV), Herpes simplex virus (HSV) and other (Varicella-Zoster virus infection, Syphilis, Parvovirus B19, Hepatitis B), Aim& Objective: Detection of Toxoplasma IgM antibodies of BOH patients attending Integral Institute of Medical Sciences& Research Lucknow and to corelate present study finding with other National& International level data on IgM Toxoplasma studies. Method: Prospective cross-sectional study was conducted on pregnant female with fetal congenital malformation in present pregnancy and pregnant females with Bad obstetric history (BOH) attending Integral Institute of Medical Sciences& research using ELISA test for Toxoplasma IgM antibodies. The research was approved by institutional ethical committee. Result: In our study, the overall seroprevalence of Toxoplasma IgM antibody was 7.40 % (6/81) Out of 81 majority of patients (43.20 %) belonged to non-pregnant patients with BOH, followed by (32.09 %) patients belonged to pregnant patients with BOH and (24.69 %) patients belonged to patients who came for their first antenatal check-up. Conclusion: Our study gave us a clue about IgM status i. e. recent infection, made us wiser in formulating control measures for the prevention of Toxoplasmosis.