Current Update on Management of Infantile Colic

Infant colic is a troubling condition for both parents and pediatrician, but it is benign and self-limiting. About 40 % infants experience colic and it resolves between 12-16 week of life. ROME III and IV criteria are used for diagnosing infantile colic, but ROME IV is more specific for research purposes. The cause of colic is unknown but some hypotheses were proposed such as bile acid immaturity, microbial alterations and immaturity of gastrointestinal motility. Parental reassurance is the key of management of this condition, other therapies such as dietary modification, pharmacological and other approaches were not proven to be effective. Probiotics (Lactobacillus reuteri DSM 17938) are proven to reduce the symptoms and can prevent the colic. Other strains are still need further studies to be recommended.