Experimental Evaluation of Green Approach in Organic Synthesis

Unlimited use of chemical and disposal of chemical waste makes the environment polluted. To avoid or minimize the damage of environment; green techniques are used in various organic synthesis. Green techniques have important environmental and economic advantages over traditional synthetic processes. Herein, some green techniques such as multi-component reactions, green solvents, green catalysis, microwave and ultra-sonications reactions are discussed. The development of the concepts for Green Chemistry and the main principles of this field are reviewed. Examples of the application of these principles in different areas of chemistry are included. The frequently used alternative solvents (green solvents – water, PEG, per fluorinated solvents, supercritical liquids) in preparative organic chemistry are described. The present and the future developments of green chemistry in education and organic chemical technology are considered. Green chemistry is one of the most important research topics and has attracted most of the researchers. The use of green chemistry in chemical synthesis can reduce the damage to the environment occurred by the use of hazardous chemicals. With the increasing demands in relation to environmental protection, the use of green chemistry approach in organic synthesis is desirable. The design of promising Lewis acid catalysts has attracted considerable interest inorganic synthesis because of their unique Catalytic performances in organics reactions. Cardiovascular diseases have been the principal cause of death in many developing countries and disability in industrialized nations and are among the syndromes most commonly encountered in clinical practice. The major diagnosis of heart failure carries a risk of mortality comparable to that of the major malignancies. Heart failure occurs when cardiac output is insufficient to meet the demands of tissue perfusion and may primarily be due to systolic or diastolic dysfunction.