Investigate of Analgesic Activity of Ethanolic Extract of Leaves of Epiphyllum Oxypetalum

Pain as a sensory modality; represent a symptom for diagnosing various diseases and its associated conditions. Although it acts as a sensory modality in drawing attention to tissue injury, it is associated with poor quality of life and socioeconomic burden to the victim. Conventional synthetic drugs that are used to manage pain are not readily available and are associated with adverse effects. Thus, the use of herbal medicine from medicinal plants is an age-old practice used by many communities to cure diseases. These medicinal plants are known to contain phytochemical compounds capable of relieving pain and healing diseases. Epiphyllum oxypetalum is a species of cactus and one of the most commonly grown of the Epiphyllum species. It is one of the under-utilized resources available in the tropical regions of the globe and can be used as a substitute for digitalis. The Shoshone Indian tribe calls the night blooming Cereus Pain in the heart and used it for heart pain. Scanty work was reported on the phytochemical properties of leaf extract and no documented research work was reported on its leaf for analgesic activity. Thus, the present investigation was carried out to access the analgesic activity, phytochemical constituents and analgesic potentials of leaf extracts. Phytochemical analysis of Epiphyllum oxypetalum showed the presence of saponins, phenolic compounds, steroids, glycosides, tannins, terpenoids, and resins while reducing sugars, alkaloids, flavonoids, sterols, phlorotannins and acidic compounds were absent.