Statins - A Thriving New Era in Periodontal Therapy

It is a well-established fact today that many variants of periodontal disease are essentially infections to the periodontal structures. Numerous technique�s have been tried to correct the periodontal attachment and bone loss caused due to the disease. Introduction of an agent for regenerative therapy that hampers tissue destruction and enhances the regenerative capacity of periodontal tissues is required. Statins are group of drugs that are known to exhibit antibone resorbing properties by upregulating the bone morphogenic proteins and blocking the intermediate metabolites of the mevalonate pathway. Hence, it has been widely accepted to increase the bone mineral density and effective for periodontal regeneration. This article reviews the role of statins as a therapeutic agent in the treatment of periodontal diseases.